HPV Papers: 28 and Counting

There are thousands of stories of girls, boys, and families that have been devastated by adverse events related to the vaccine targeting HPV. The pictures above are just a fraction. Many media sources seek to paint the complex adverse event stories after HPV vaccine as a psychosomatic hysteria. Are there honest scientists investigating the potential of harm from this vaccines? Below are many published papers with questions about the Gardasil vaccine causing serious adverse events. I’ve compiled this list – which is not meant to be exhaustive – to demonstrate that there are a lot of questions about this vaccine. Despite real safety concern doctors and media continue to push hard for families to accept this vaccine, and some states are seeking mandates for all school children of this vaccine which targets a sexually transmitted illness. Other states are reducing the age of consent in an effort to get young teens to accept this vaccine without their parents knowledge. Parents are faced with a choice. What do I do? Who do I trust? How do I discuss this with my pre-teen?

1. “Cardiac arrest following HPV Vaccination”. Yehuda Shoenfeld. Published October 7, 2019.

Full Citation: Shani Dahan, Yahel Segal, Amir Dagan, Yehuda Shoenfeld, Michael Eldar (2019) Cardiac arrest following HPV Vaccination. Clin Res Trials 5: DOI: 10.15761/CRT.1000279

296 deaths recorded in VAERS up to 2.5.2017.

https://www.oatext.com/cardiac-arrest-following-hpv-vaccination.php

2. “Postural tachycardia syndrome (POTS) after vaccination with Gardasil” February 2010. A case study of a previously healthy 14 year old girl.

Full citation: Blitshteyn, S. (2010). Postural tachycardia syndrome after vaccination with Gardasil. European Journal of Neurology, 17(7), e52–e52. doi:10.1111/j.1468-1331.2010.03021.x 

https://sci-hub.tw/10.1111/j.1468-1331.2010.03021.x

3. “Myasthenia gravis [MG] following human papillomavirus vaccination: a case report”. “This case report implies that the HPV vaccination may cause MG. Other neurological manifestations may occur owing to unexpected abnormal autoimmune responses such as autonomic dysfunction and pain. It is important to inform patients prior to inoculation and observe the occurrence of abnormal symptoms. Moreover, it is critical to intervene promptly and treat the patient when fatal deterioration is observed. We believe that additional studies are needed to assess the possible causal relationship between the HPV vaccine and neurological complications and to evaluate the safety of the vaccine.”

Fuill citation: Chung, J.Y., Lee, S.J., Shin, B. et al. Myasthenia gravis following human papillomavirus vaccination: a case report. BMC Neurol18, 222 (2018). https://doi.org/10.1186/s12883-018-1233-y

https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-018-1233-y

4. “Postural Orthostatic Tachycardia [POTS] With Chronic Fatigue After HPV Vaccination as Part of the “Autoimmune/Auto-inflammatory Syndrome Induced by Adjuvants”: Case Report and Literature Review”. 28 December 2018.

Full citation: Chung, J.Y., Lee, S.J., Shin, B. et al. Myasthenia gravis following human papillomavirus vaccination: a case report. BMC Neurol18, 222 (2018). https://doi.org/10.1186/s12883-018-1233-y

https://journals.sagepub.com/doi/full/10.1177/2324709614527812

5. “Severe somatoform and dysautonomic syndromes after HPV vaccination: case series and review of literature” 

“Recently, a collection of symptoms, indicating nervous system dysfunction, has been described after HPV vaccination. We retrospectively described a case series including 18 girls (aged 12–24 years) referred to our ‘‘Second Opinion Medical Network’’ for the evaluation of ‘‘neuropathy with autonomic dysfunction’’ after HPV vaccination. All girls complained of long-lasting and invalidating somatoform symptoms (including asthenia, headache, cognitive dysfunctions, myalgia, sinus tachycardia and skin rashes) that have developed 1–5 days (n = 11), 5–15 days (n = 5) and 15–20 days (n = 2) after the vaccination. These cases can be included in the recently described immune dysfunction named autoimmune/inflammatory syndrome induced by adjuvants (ASIA).”

Full citation: Palmieri, B., Poddighe, D., Vadalà, M., Laurino, C., Carnovale, C., & Clementi, E. (2016). Severe somatoform and dysautonomic syndromes after HPV vaccination: case series and review of literature. Immunologic Research, 65(1), 106–116. doi:10.1007/s12026-016-8820-z 

https://sci-hub.tw/10.1007/s12026-016-8820-z

6. “AUTOIMMUNE NEUROMYOTONIA FOLLOWING HUMAN PAPILLOMA VIRUS VACCINATION”. “In conclusion, this case points out the possible occurrence of severe, but rare, neurological immunemediated complications after HPV4 vaccination.”

Full citation: Cerami, C., Corbo, M., Piccolo, G., & Iannaccone, S. (2013). Autoimmune neuromyotonia following human papilloma virus vaccination. Muscle & Nerve, 47(3), 466–467. doi:10.1002/mus.23648 

https://sci-hub.tw/10.1002/mus.23648

7. “Brachial plexus neuritis following HPV vaccination”. “…clinicians should be aware that consecutive injections may theoretically potentiate the neurological complications observed after the first or second injection.”

Full citation: Debeer, P., De Munter, P., Bruyninckx, F., & Devlieger, R. (2008). Brachial plexus neuritis following HPV vaccination. Vaccine, 26(35), 4417–4419. doi:10.1016/j.vaccine.2008.06.074 

https://sci-hub.tw/10.1016/j.vaccine.2008.06.074

8. “Demyelinating disease and polyvalent human papilloma virus vaccination”. “We encountered two cases whose initial presentation of CNS demyelination followed in close time relationship the administration of Gardasil vaccine and we discuss their possible association.”

Full citation: Chang, J., Campagnolo, D., Vollmer, T. L., & Bomprezzi, R. (2010). Demyelinating disease and polyvalent human papilloma virus vaccination. Journal of Neurology, Neurosurgery & Psychiatry, 82(11), 1296–1298. doi:10.1136/jnnp.2010.214924 

https://sci-hub.tw/10.1136/jnnp.2010.214924

9. “CNS demyelination and quadrivalent HPV vaccination”, 2009. “”Since commencement of this program, five individuals aged 16–25 years have presented to the Multiple Sclerosis Clinics at the University of Sydney and St Vincent’s Hospital with a CNS inflammatory disorder occurring within 28 days of a Gardasil® immunization. We consider that these cases are noteworthy not only because of their temporal association with immunization but also because of the atypical or multifocal nature of the presentations.”

Full citation: Sutton, I., Lahoria, R., Tan, I., Clouston, P., & Barnett, M. (2009). CNS demyelination and quadrivalent HPV vaccination. Multiple Sclerosis Journal, 15(1), 116–119. doi:10.1177/1352458508096868 

https://sci-hub.tw/10.1177/1352458508096868

10. “Neuromyelitis optica following human papillomavirus vaccination”. “Discussion. We regard these 4 cases of NMO occurring in temporal association with qHPV-vac vaccinations noteworthy.”

Full citation: Menge, T., Cree, B., Saleh, A., Waterboer, T., Berthele, A., Kalluri, S. R., … Kieseier, B. C. (2012). Neuromyelitis optica following human papillomavirus vaccination. Neurology, 79(3), 285–287. doi:10.1212/wnl.0b013e31825fdead 

https://sci-hub.tw/10.1212/WNL.0b013e31825fdead

11. “Human Papillomavirus Epitope Mimicry and Autoimmunity: The Molecular Truth of Peptide Sharing” “Specifically, the present data indicate that, via cross-reactivity, the immune responses that follow HPV infections/active immunizations might lead to premature ovarian failure, oocyte DNA damage, lupus manifestations, susceptibility to breast/ovarian cancer, neuropsychiatric diseases, hypotension and dysregulation of blood pressure, cardiac disorders, and, even, sudden death. Clinically, such a vast cross-reactivity potential explains the multiple autoimmune disease syndromes that can follow infections/active immunization.”

Full citation: Kanduc, D., & Shoenfeld, Y. (2019). Human Papillomavirus Epitope Mimicry and Autoimmunity: The Molecular Truth of Peptide Sharing. Pathobiology, 1 11. doi:10.1159/000502889 

https://sci-hub.tw/10.1159/000502889

12. “Current Safety Concerns with Human Papillomavirus Vaccine: A Cluster Analysis of Reports in VigiBase®”. “Our analysis of global reports of suspected AEs following HPV vaccination has revealed a large number of reports with a pattern of AEs, including headache, dizziness, fatigue and syncope, distinguished from more common AEs by their serious nature (causing/prolonging hospitalisation and/or disabling/incapacitating), resulting in an impact on the quality of life of the patient. Included in this group are reports that have been labelled as POTS, CFS, and CRPS, but the majority of the reports lack explicit diagnoses.”

Full citation: Chandler, R. E., Juhlin, K., Fransson, J., Caster, O., Edwards, I. R., & Norén, G. N. (2016). Current Safety Concerns with Human Papillomavirus Vaccine: A Cluster Analysis of Reports in VigiBase®. Drug Safety, 40(1), 81–90. doi:10.1007/s40264-016-0456-3  

https://sci-hub.tw/10.1007/s40264-016-0456-3

13. “Vaccinations and secondary immune thrombocytopenia with antiphospholipid antibodies by human papillomavirus vaccine”. “The importance of case reports can be summarized in three points. First, a case report may act to raise the awareness of physicians to adverse events following immunization (AEFI), including autoimmune diseases. Secondly, in order to determine the prevalence of AEFIs it is of outmost importance that physicians be able to identify and report such occurrences. Thirdly, growing evidence implies that there might be a subgroup of individuals that are susceptible to post-vaccination autoimmunity induction.”

Full citation: Bizjak, M., Bruck, O., Kanduc, D., Praprotnik, S., & Shoenfeld, (2016). Vaccinations and secondary immune thrombocytopenia with antiphospholipid antibodies by human papillomavirus vaccine. Seminars in Hematology, 53, S48–S50.  doi:10.1053/j.seminhematol.2016.04.014 

https://sci-hub.tw/10.1053/j.seminhematol.2016.04.014

14. “Autonomic dysfunction and HPV immunization: an overview”. “This article reviews the case series reported from several countries describing patients with suspected severe side effects to the HPV vaccines. The described symptom clusters are remarkably similar and include disabling fatigue, headache, widespread pain, fainting, gastrointestinal dysmotility, limb weakness, memory impairment episodes of altered awareness, and abnormal movements. This constellation of symptoms and signs has been labeled with different diagnoses such as complex regional pain syndrome (CRPS), postural orthostatic tachycardia syndrome (POTS), small fiber neuropathy (SFN), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), or fibromyalgia. It is known that autoimmunity and autoantibodies are present in a subset of patients with CRPS, POTS, SFN, ME/CFS, and fibromyalgia. This article proposes that vaccine-triggered, immune-mediated autonomic dysfunction could lead to the development of de novo post-HPV vaccination syndrome possibly in genetically susceptible individuals.”

Full citation: Blitshetyn, S., Brinth, L., Hendrickson, J. E., & Martinez-Lavin, M. (2018). Autonomic dysfunction and HPV immunization: an overview. Immunologic Research. doi:10.1007/s12026-018-9036-1 

https://sci-hub.tw/10.1007/s12026-018-9036-1

15. “Hidden Toxicity of Human Papillomavirus Vaccine Ingredients”. Introduction: “Recent publications originating from Italy, Japan, Australia, Columbia, India, Ireland, Denmark, Mexico, Norway, Sweden, Canada, France, the USA, and the United Kingdom have reported post-HPV vaccination phenomena that share overlapping clinical features with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME), fibromyalgia (FM), postural orthostatic tachycardia syndrome (POTS), complex regional pain syndrome (CRPS), small fiber neuropathy (SFN), and autonomic dysfunction (AD) [1,2]. Typical symptoms include (but are not limited to) prolonged generalized fatigue, chronic headaches, widespread generalized pain, tremors, orthostatic fainting, postural tachycardia, alterations in gastrointestinal motility, gait disturbance, anxiety, paresthesia’s, sleep disturbance, learning impairment, difficulty in concentration, and other cognitive phenomena [16]. These reported phenomena have created hesitation by some parents to have HPV vaccination administered to their teenage children. The following case history adds to the growing list of adverse HPV vaccine-induced reports and provides insight into disease causation via an in-depth analysis of the complex HPV vaccine ingredients.”

Conclusion: “The controversy surrounding HPV vaccine-induced illness is no longer one of methodology, it is one of terminology. HPV vaccine-induced illness is a genuinely novel and legitimate entity unto itself that shares clinical features with the ever-expanding list of neurologic fatiguing syndromes. This illness is undoubtedly caused by multiple toxic disturbances of the body’s biochemistry induced by emulsifiers, surfactants, and immune-stimulatory complexes. HPV vaccine-induced illness is not a psychogenic reaction fueled by the news media and attorneys, nor is it one of primary autoimmune reactivity. It is no longer appropriate to make the statement “if you don’t have ‘A’ (something in the textbook), then you don’t have ‘B’ (something new), i.e. you have nothing”. In a recent publication by Ikeda and colleagues, new patients with HPV vaccine related ailments have not appeared after the Japanese Ministry of Public Health withdrew its vaccine recommendation more than four years ago [24]. HPV vaccine-induced illness exemplifies the fact that the complexity of nature far transcends man’s ingenuity.”

Full citation: Brawer AE (2019) Hidden Toxicity of Human Papillomavirus Vaccine Ingredients. J Rheum Dis Treat 5:075. doi.org/10.23937/2469-5726/1510075

https://www.clinmedjournals.org/articles/jrdt/journal-of-rheumatic-diseases-and-treatment-jrdt-5-075.php

16. “Acute disseminated encephalomyelitis following vaccination against human papilloma virus”. A case report of severe encephalitis evolving shortly after administration of a new vaccine against human papilloma virus (HPV) in a 20 year old previously healthy woman.

Full citation: Wildemann, B., Jarius, S., Hartmann, M., Regula, J. U., & Hametner, C (2009). ACUTE DISSEMINATED ENCEPHALOMYELITIS FOLLOWING VACCINATION AGAINST HUMAN PAPILLOMA VIRUS. Neurology, 72(24), 2132–2133. doi:10.1212/wnl.0b013e3181aa53bb 

https://sci-hub.tw/10.1212/WNL.0b013e3181aa53bb

17. “Vaccine-induced autoimmunity: the role of molecular mimicry and immune crossreaction”. “It is therefore pertinent for the scientific community to seriously address public concern of adverse effects of vaccines to regain public trust in these important medical interventions. Such adverse reactions to vaccines may be viewed as a result of the interaction between susceptibility of the vaccinated subject and various vaccine components. Among the implicated mechanisms for these reactions is molecular mimicry. Molecular mimicry refers to a significant similarity between certain pathogenic elements contained in the vaccine and specific human proteins. This similarity may lead to immune crossreactivity, wherein the reaction of the immune system towards the pathogenic antigens may harm the similar human proteins, essentially causing autoimmune disease. In this review, we address the concept of molecular mimicry and its application in explaining post vaccination autoimmune phenomena. We further review the principal examples of the influenza, hepatitis B, and human papilloma virus vaccines, all suspected to induce autoimmunity via molecular mimicry.” 

Full citation: Segal, Y., & Shoenfeld, Y. (2018). Vaccine-induced autoimmunity: the role of molecular mimicry and immune crossreaction. Cellular & molecular immunology15(6), 586–594. https://doi.org/10.1038/cmi.2017.151

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078966/

18. “Peripheral Sympathetic Nerve Dysfunction in Adolescent Japanese Girls Following Immunization with the Human Papillomavirus Vaccine”. The post HPV reactions of 44 girls in Japan are discussed.

Full citation: Kinoshita, T., Abe, R., Hineno, A., Tsunekawa, K., Nakane, S., & Ikeda, S. (2014). Peripheral Sympathetic Nerve Dysfunction in Adolescent Japanese Girls Following Immunization with the Human Papillomavirus Vaccine. Internal Medicine, 53(19), 2185–2200. doi:10.2169/internalmedicine.53.3133 

https://sci-hub.tw/10.2169/internalmedicine.53.3133

19. “Long-lasting adverse events following immunization with Cervarix”. 21 page report December 2015. The Nederlands received 1271 reports of adverse events following Cervarix HPV vaccine. “Lareb has received a substantial number of reports concerning long-lasting AEFIs after vaccination with Cervarix®. The most frequently reported long-lasting AEFI was fatigue. This follow-up survey showed that these long-lasting, medically unexplained symptoms have considerable impact on the lives of these girls and the lives of their family members. Also no cause for the complaints could be found and most of the girls were not recovered at the moment of last contact with Lareb.”

https://databankws.lareb.nl/Downloads/Lareb_rapport_HPV_dec15_03.pdf

20. “Human Papilloma Virus Vaccines and Gastrointestinal Motility Disorders”. 2015. A WHO study examining 21 reports from various countries concluding “further investigation is warranted.”

Full citation: Chandler, Rebecca & Hult, S. & Caduff-Janosa, Pia. (2015). Human Papilloma Virus Vaccines and Gastrointestinal Motility Disorders. 976-977.

https://www.researchgate.net/publication/292591837_Human_Papilloma_Virus_Vaccines_and_Gastrointestinal_Motility_Disorders

21. “Human papilloma virus vaccination and dysautonomia: Considerations for autoantibody evaluation and HLA typing”. 2016. “In summary, the case series recently published by Vaccine raises a potential hypothesis for further study of any relationship between HPV vaccination and dysautonomia in a subset of vaccinated patients.”

Full citation: Hendrickson, J. E., & Tormey, C. A. (2016). Human papilloma virus vaccination and dysautonomia: Considerations for autoantibody evaluation and HLA typing. Vaccine, 34(38), 4468. doi:10.1016/j.vaccine.2016.05.029 

https://sci-hub.tw/10.1016/j.vaccine.2016.05.029

22. “Autoimmunity against the β2 adrenergic receptor and muscarinic-2 receptor in complex regional pain syndrome [CRPS]”. While there is no mention of vaccines in this paper, the conclusion would point to a closer examination: “Taken together, the identification of receptor-binding autoantibodies directed against the muscarinic M2R and the adrenergic b2AR provides clear evidence of an autoimmune etiology of CRPS.”

Full citation: Kohr, D., Singh, P., Tschernatsch, M., Kaps, M., Pouokam, E., Diener, M., … Blaes, F. (2011). Autoimmunity against the β2 adrenergic receptor and muscarinic-2 receptor in complex regional pain syndrome. Pain, 152(12), 2690–2700. doi:10.1016/j.pain.2011.06.012 

https://sci-hub.tw/10.1016/j.pain.2011.06.012

23. “Post Gardasil POTS and Thiamine Deficiency”. Girls suffering after Gardasil vaccine tested and found to be extremely thiamin deficient resulting in this conclusion: “These three factors, Genetics, Stress and Nutrition can be seen as three interlocking circles, all of which overlap at the center. “

Derrick Lonsdale MD. Hormones MatterTM is conducting research on the side effects and adverse events associated with Gardasil and its counterpart Cervarix. If you or your daughter has had either HPV vaccine, please take this important survey. The Gardasil Cervarix HPV Vaccine Survey.

http://www.hormonesmatter.com/post-gardasil-pots-thiamine-deficiency/

24. “Detection of human papillomavirus L1 gene DNA fragments in postmortem blood and spleen after Gardasil® vaccination—A case report”. “CONCLUSION: Detection of HPV-16 L1 gene DNA fragments in non-Bconformation in postmortem blood and spleen from a person who died suddenly and unexpectedly 6 months after quadrivalent HPV vaccination has not been previously reported and warrants further investigation. “

Sin Hang Lee, Advances in Bioscience and Biotechnology, 2012, 3, 1214-1224. https://file.scirp.org/pdf/ABB20120800017_19392756.pdf

25. “Male Impotence following Gardasil”. In addition to male impotence, this article highlights the drop in birth rate amongst women from 25-29. Birth rates down from 118/100,000 in 2007 to 105/100,000 in 2015.

https://helenlobato.com/2020/01/15/male-impotence-following-gardasil/

26. “Premature ovarian failure 3 years after menarche in a 16-year-old girl following human papillomavirus vaccination”.

Full citation: Little DT, Ward HRGPremature ovarian failure 3 years after menarche in a 16-year-old girl following human papillomavirus vaccination Case Reports  2012;2012:bcr2012006879.

https://casereports.bmj.com/content/2012/bcr-2012-006879.abstract

27. “Death after Quadrivalent Human Papillomavirus (HPV) Vaccination: Causal or Coincidental?” Post mortem brain tissue of two young women leads researchers to conclude: Our study suggests that HPV vaccines containing HPV-16L1 antigens pose an inherent risk for triggering potentially fatal autoimmune vasculopathies.”

Full citation: Tomljenovic L, Shaw CA (2012) Death after Quadrivalent Human Papillomavirus (HPV) Vaccination: Causal or Coincidental? Pharmaceut Reg Affairs S12:001. doi: 10.4172/2167-7689.S12-001

https://mednat.news/vaccini/cancro_utero_vaccino=morte.pdf

28. “A 16-Year-Old Girl With Bilateral Visual Loss and Left Hemiparesis Following an Immunization Against Human Papilloma Virus.”

Full citation: DiMario, F. J., Hajjar, M., & Ciesielski, T. (2010). A 16-Year-Old Girl With Bilateral Visual Loss and Left Hemiparesis Following an Immunization Against Human Papilloma Virus. Journal of Child Neurology, 25(3), 321–327. https://doi.org/10.1177/0883073809349322

https://journals.sagepub.com/doi/abs/10.1177/0883073809349322#articleCitationDownloadContainer

BOOKS:

Gardasil: Fast Tracked and Flawed, by Helen Lobato, documents the early history of cervical cancer and tracks its progression from a disease of obscurity to one of mainstream prominence. It includes the stories of vaccinated girls and boys who remain ill after receiving a vaccine purported to prevent a disease they were most unlikely to get. It records the voices of dissenters and resisters who call for an inquiry into HPV vaccines approved for use after a relentless propaganda campaign promoting a vaccine against a virus that many had never heard of.

This 140 page book is an in-depth investigation exposes cracks in the pharmaceutical industry and highlights the problems that arise when government regulators and corporate interests are prioritised ahead of patient safety, independent science and common sense.

The HPV Vaccine On Trial: Seeking Justice For A Generation Betrayed by Mary Holland, Kim Mack Rosenberg, and Eileen Iorio. A Groundbreaking Guide to the HPV Vaccine and the science, safety, and business Behind It.

Cancer strikes fear in people’s hearts around globe. So the appearance of a vaccine to prevent cancer–as we are assured the human papillomavirus (HPV) vaccine will–seemed like a game-changer. Since 2006, over eighty countries have approved the vaccine, with glowing endorsements from the world’s foremost medical authorities. Bringing in over $2.5 billion in annual sales, the HPV vaccine is a pharmaceutical juggernaut. Yet scandal now engulfs it worldwide.

The HPV Vaccine on Trial is a shocking tale, chronicling the global efforts to sell and compel this alleged miracle. The book opens with the vaccine’s invention, winds through its regulatory labyrinths, details the crushing denial and dismissal of reported harms and deaths, and uncovers the enormous profits pharma and inventors have reaped. Authors Holland, Mack Rosenberg, and Iorio drill down into the clinical trial data, government approvals, advertising, and personal accounts of egregious injuries that have followed in countries as far-flung as Japan, Australia, Colombia, India, Ireland, the U.K. and Denmark. The authors have written an unprecedented exposé about this vaunted vaccine.

Written in plain language, the book is for everyone concerned – parents, patients, doctors, nurses, scientists, healthcare organizations, government officials, and schools. Ultimately, this book is not just about the HPV vaccine, but about how industry, government, and medical authorities may be putting the world’s children in harm’s way.

Please feel free to share your story and/or leave links to other papers in the comments. And feel free to let me know if you catch any mistakes in editing. Thank you.

Becky Hastings, avid follower of Jesus Christ, wife, mother, grandmother, health seeker and reporter. Seeking truth can be challenging, and sometimes confusing, but far more rewarding than staying ignorant.

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