This blog post is a list of science references that demonstrate the DTaP/TDaP and DTP effectiveness. If you are pregnant, please also read my blogs specifically directed toward pregnant women who are being pushed to get the TDaP to “protect their baby and pass on  antibodies to whooping cough” and also pushed to get the flu vaccine. 

A 1991 study published in The National Center for Biotechnology Information reveals that the United Stated government has known since 1991 that a link between DTP and microcephaly exists.

Commentary:
http://www.march-against-monsanto.com/1991-government-document-confirms-tdap-vaccine-causes-microcephaly/

Actual study:
http://www.ncbi.nlm.nih.gov/books/NBK234367/

The DTP whole-cell pertussis vaccine was withdrawn in 1996 and replaced with the acellular pertussis in two versions: DTaP for babies and young children and the TDaP for older children and adults. A series of four shots is recommended for babies by the CDC, at 2, 4, 6, and 15-18 months. In 2013 the CDC implemented a policy of recommending every Pregnant woman be given a TDaP shot in every pregnancy, no matter when they last had a shot, despite the risk to the unborn baby, the contraindications of giving TDaP to children, and lack of safety studies.

From the National Vaccine Information Center:

Whole-cell DPT contains B. pertussis bacteria heat and chemically treated as well as significant amounts of endotoxin (capable of killing animals and humans on its own). There is less endotoxin in DTaP, however both DPT and DTaP contain aluminum adjuvants. Aluminum can kill brain cells and make the blood brain barrier more permeable

Even though the acellular DTaP vaccine is believed to be less reactive than the whole cell DPT vaccine, NVIC still receives reports of serious reactions following DTaP vaccination that are consistent with symptoms and injuries known to be associated with DPT vaccine, including high pitched screaming, fever over 103F, collapse/shock (hypotonic/hyporesponsive episode), convulsions, and encephalopathy.

Infants and children, who have demonstrated one or more of these symptoms following DTAP vaccination (or any other vaccination), should be carefully evaluated by one or more health care professionals before more DTaP or other vaccines are given. If you, as a parent, are concerned that continuing vaccination would harm your child and a doctor is insisting more vaccines be given without your voluntary consent, you should contact another trusted health care professional for a second opinion. If your child has experienced health deterioration after previous vaccinations, it is important listen to your intuition and become totally comfortable before proceeding with more vaccination. http://www.nvic.org/faqs/vaccines-infectious-disease.aspx

The chances of getting pertussis worldwide according to data taken from 2014 is about 1 in 50,000. Pertussis causes the most complications to children under 3 months. If a baby is given vaccines according to the CDC schedule, they aren’t fully vaccinated until 6+ months (DTaP at 2, 4 and 6 months). Children who get pertussis over one year of age usually fully recover with no lasting problems. Vitamin C therapy has been shown to reduce the severity and duration of pertussis in infants.

According to the Daptacel vaccine insert, (Sanofi Pasteur’s diphtheria, tetanus, and pertussis vaccine) many serious adverse reactions were reported including bronchiolitis, pneumonia, sepsis (life threatening blood infection), meningitis, and pertussis. 1 in 431 experienced seizures after receiving the vaccine. “Systemic reactions that occurred in >50% of subjects following any dose [of Daptacel]  included fussiness/irritability, inconsolable crying, and decreased activity/lethargy. Fever ≥38.0°C occurred in 6-16% of US subjects, depending on dose number.”

Pentacle (Sanofi Pasteur’s vaccine which includes diphtheria, tetanus, pertussis, IPV/polio, and HIB) had a 1 in 25 serious reaction rate according to one of the studies. The top reported reactions were pneumonia, asthma, bronchiolitis, gastroenteritis, and dehydration. 1 out of 1,196 died (they aren’t sure if its related or not, but that’s the facts and the potential risks). “A total of 5 deaths occurred during Studies 494-01, 494-03, 5A9908 and P3T06:”

Pediarix (Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B (Recombinant) and Inactivated Poliovirus Vaccine by GSK) reports reactions of seizures, bronchiolitis, sepsis, and gastroenteritis. 1 in 33 got a chronic illness like diabetes or asthma and 1 in 1618 died.

A good research article documenting how vaccination with DTaP and TDap contribute to increased rates of whooping cough.

“Thus, we conclude that aP vaccination interferes with the optimal clearance of B. parapertussis and enhances the performance of this pathogen. Our data raise the possibility that widespread aP vaccination can create hosts more susceptible to B. parapertussis infection.”

Acellular pertussis vaccination facilitates Bordetella parapertussis infection in a rodent model of bordetellosis, Proc Biol Soc July 2010, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880100/

Neurological Complications of Pertussis Immunization has been known since 1958 when this paper was published, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025848/

DPT Vaccine and Chronic Nervous System Dysfunction: A New Analysis, http://www.nap.edu/catalog.php?record_id=9814#toc /

Pertussis toxin is required for pertussis vaccine encephalopathy, published in 1985, http://www.ncbi.nlm.nih.gov/…/pdf/pnas00364-0469.pdf /

Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma, Journal of Allergy and Clinical Immunology, March 2008, http://www.jacionline.org/…/S0091-6749(07)02379-2/fulltxt /

Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States, J Manipulative Physiol There, February 2000, ‪http://www.ncbi.nlm.nih.gov/pubmed/10714532

Pertussis outbreak in Washington 2012. CDC reports that 76% of cases were 100% vaccinated and up to date on boosters and 93% of children were vaccinated for DTap. In this sample only 4% of children were unvaccinated. 2012, http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6128a1.htm

Acellular pertussis vaccination facilitates Bordetella parapertussis infection, Proc Biol Sci, July 2010, http://www.ncbi.nlm.nih.gov/pubmed/20200027

Acellular Pertussis vaccine protects against disease but fail to prevent infection and transmission in a nonhuman primate model, Proceedings of the National Academy of Sciences of the Unites States of America, October 2013, http://www.pnas.org/content/111/2/787

Clinical presentation of pertussis high amongst fully immunized children in Lithuania, BMC Infectious Diseases, May, 2005, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177947/

Pertussis outbreak in US elementary school with high vaccination coverage, Pediatric Infect Dis J, December 2001, http://www.ncbi.nlm.nih.gov/pubmed/11740314

The pertussis vaccine is shown to be not very effective:

Unexpectedly Limited Durability of Immunity Following Acellular Pertussis Vaccination in Pre-Adolescents in a North American Outbreak , Clinical Infectious Diseases Advance Access, March 2012, http://cid.oxfordjournals.org/content/early/2012/03/13/cid.cis287.full.pdf

Whooping cough caused by Bordetella pertussis and Bordetella parapertussis in an immunized population, JAMA, August 1998, http://www.ncbi.nlm.nih.gov/pubmed/9718056

DPT Vaccine and Chronic Nervous System Dysfunction: A New Analysis, IOM, 1994, http://www.nap.edu/catalog/9814/dpt-vaccine-and-chronic-nervous-system-dysfunction-a-new-analysis

Pertussis (Whooping Cough)

FDA study helps provide an understanding of rising rates of whooping cough and response to vaccination, FDA NEWS RELEASE, Nov. 27, 2013, http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm376937.htm

36 Abstracts with Vaccination: Diphtheria-Pertussis-Tetanus Research, http://www.greenmedinfo.com/anti-therapeutic-action/vaccination-diphtheriapertussis-tetanus

This article clearly describes vaccine failure because a pertussis outbreak occurred in mostly vaccinated children:

Sustained Transmission of Pertussis in Vaccinated, 1-5-Year-Old Children in a Preschool, Florida, USA, Emerging Infectious Diseases, February, 2016, http://wwwnc.cdc.gov/eid/article/22/2/pdfs/15-0325.pdf

Most of the people who got whooping cough in San Diego County were up to date with their immunizations, according to county data. Of the 621 people who contracted the illness, 85 percent had all their preventative shots — calling into question the efficacy of the vaccine.

Immunized People Getting Whooping Cough. KPBS, June 12, 2014, http://www.kpbs.org/news/2014/jun/12/immunized-people-getting-whooping-cough/